FC Porto host Napoli at the Estádio do Dragão on Wednesday night in the UEFA Champions League, with the hosts desperate for a first European point of the season. Porto have won all ten of their Liga Portugal games but lost all three Champions League games, while Napoli sit 22nd on three points after the 4-3 win over Bodø/Glimt.
This FC Porto vs Napoli prediction matters for bettors because it pits the best domestic form in Portugal against a Napoli side carrying a long injury list and a seven-game winless run away from home in the Champions League.
FC Porto vs Napoli Match Preview
Porto’s recent run has been split in two: a 4-0 win over Estoril, a 1-0 League Cup win over Académico de Viseu and a 1-0 win at Gil Vicente domestically, but a 1-0 defeat to PSV Eindhoven and a 3-2 defeat at Real Betis in Europe. Napoli, meanwhile, lost 2-0 at Juventus in their last game but had won 4-1 at Monza and drawn 3-3 with Roma, with the 4-3 win over Bodø/Glimt their only European victory.
Team Recent Form
FC Porto (most recent first): W-W-W-L-L — Porto 4-0 Estoril (Liga Portugal); Porto 1-0 Académico de Viseu (Portugal League Cup); Gil Vicente 0-1 Porto (Liga Portugal); Porto 0-1 PSV Eindhoven (Champions League); Real Betis 3-2 Porto (Champions League).
Napoli (most recent first): L-W-D-W-L — Juventus 2-0 Napoli (Serie A); Monza 1-4 Napoli (Serie A); Napoli 3-3 Roma (Serie A); Napoli 4-3 Bodø/Glimt (Champions League); Venezia 1-0 Napoli (Serie A).
Key Stats
- Porto have won all ten of their Liga Portugal games this season, scoring 25 goals and conceding just four, but have lost all three Champions League games.
- Napoli are winless in seven Champions League away games, and sit 22nd in the league-phase table on three points.
- Porto sit 34th in the league-phase table with no points and a goal difference of minus four, so a win is essential to keep their play-off hopes alive.
2-1 is our correct-score prediction: Porto’s home form should finally deliver a European win, but Napoli’s scoring form means the visitors should find the net at least once.
FC Porto vs Napoli H2H
- 20 March 2014: Napoli 2-2 Porto (Europa League, round of 16, 2nd leg; Porto won 3-2 on aggregate)
- 13 March 2014: Porto 1-0 Napoli (Europa League, round of 16, 1st leg)
- 1974-75: Napoli beat Porto 1-0 home and away (UEFA Cup, 2nd round; Napoli progressed)
The competitive record is four meetings: two Napoli wins, one Porto win and one draw. A 2013 Emirates Cup friendly and a 2015 friendly are not competitive meetings and are not listed here.
Pre Game Odds
- FC Porto win: 2.15
- Draw: 3.82
- Napoli win: 3.80
Odds via SportyTrader (best odds, checked 3 Nov 2026), pre-match and subject to change.
Team News FC Porto
Porto are without William Gomes and Vasco Sousa (both injured), and Chris Smalling, who tore the MCL in his right knee on his Porto debut. Oskar Pietuszewski is a doubt with a minor thigh problem, and Zaidu Sanusi is a doubt after limping off at half-time against Estoril with a knee issue. Martim Fernandes could return after tonsillitis.
Predicted FC Porto XI (predicted only, not confirmed): Diogo Costa; Alberto Costa, Jan Bednarek, Jakub Kiwior, Zaidu; Victor Froholdt, Pablo Rosario, Gabri Veiga; Pepê, Samu Aghehowa, Borja Sainz.
Team News Napoli
Napoli are without Alessandro Buongiorno, David Neres, Costantino Favasuli, Alisson Santos, Leonardo Spinazzola, Benoît Badiashile and Stanislav Lobotka (left ankle injury, around six weeks). Rasmus Højlund (flu), Vanja Milinković-Savić (knock/virus), Giovanni Di Lorenzo and Mathias Olivera (both muscular injuries from the Juventus game) are doubts, while Kevin De Bruyne is set to play despite a slight ankle sprain. No suspensions were verified for this tie.
Predicted Napoli XI (predicted only, not confirmed): Alex Meret; Sam Beukema, Amir Rrahmani, Rafa Marin; Matteo Politano, André-Frank Zambo Anguissa, Kevin De Bruyne, Mathias Olivera; Scott McTominay, Antonio Vergara; Rasmus Højlund.
FC Porto vs Napoli Betting Tips
Tip 1 – Result: FC Porto win. Tip 2 – Over-Under 2.5: Over 2.5 goals. Tip 3 – BTTS Yes-No: Both teams to score – Yes.
Porto’s perfect domestic form should finally translate into a European win at the Dragão, but Napoli’s attack means the visitors should score even in defeat.
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FC Porto vs Napoli prediction
Our FC Porto vs Napoli prediction is a home win, with both teams to score and over 2.5 goals.
