Real Sociedad's superior squad depth and attacking quality are expected to overwhelm a Negreir side that has struggled for goals at home. While Negreir will be organized defensively, the constant pressure from the visitors should eventually tell, leading to a comfortable away victory

The visitors' superior organization, defensive solidity, and promotion-chasing form should prove too much for an Ourense side struggling for goals and consistency. Real Oviedo's quality in both boxes and recent away performances suggest they'll secure a comfortable victory with a clean sheet.

The visitors' superior quality, professional approach, and squad depth should prove overwhelming for a CD Toledo side that will give their all but ultimately lack the technical quality to compete for 90 minutes. Sevilla's experience in these cup fixtures and need for confidence should see them secure a comfortable victory.

The visitors' superior quality, promotion-chasing form, and defensive solidity should prove too much for a Roda side struggling for goals and confidence. Granada's organized defense is likely to secure another clean sheet while their potent attack capitalizes on opportunities against a leaky home defense.

The visitors' professional approach, superior technical quality, and depth of squad should prove overwhelming for a semi-professional UD Maracena side. Valencia's La Liga attackers will likely capitalize on the massive quality gap, while their organized defense should comfortably handle any limited threats from the hosts.

The visitors' professional quality, superior fitness levels, and technical ability should prove decisive against a semi-professional Utebo side. Huesca's Segunda División experience and organized approach should secure a comfortable victory while maintaining a clean sheet against limited opposition.

The visitors' higher competitive level and professional setup should give them the edge against a determined Tropezon side. While the hosts will be buoyed by their strong home form and create scoring opportunities, Leonesa's superior quality and experience in cup competitions should see them through to a narrow victory.